Factlen ExplainerPredictive HealthEvidence PackJun 24, 2026, 11:26 PM· 6 min read

The Evidence Pack: How the Military is Using AI Wearables to Predict Infections Days Before Symptoms

A defense-funded AI algorithm known as RATE is transforming commercial smartwatches into early-warning systems, predicting infectious diseases up to 48 hours before clinical symptoms appear.

By Factlen Editorial Team

Military Readiness Planners 40%Medical Researchers 40%Privacy Advocates 20%
Military Readiness Planners
Focus on maintaining operational capacity and preventing unit-wide outbreaks.
Medical Researchers
Focus on the empirical validation of predictive models and the shift to proactive medicine.
Privacy Advocates
Focus on the implications of continuous biometric monitoring and data ownership.

What's not represented

  • · Civilian Healthcare Workers
  • · Consumer Wearable Manufacturers

Why this matters

The ability to predict an infection days before a person feels sick could fundamentally change how humanity manages pandemics. By transitioning this military technology to civilian healthcare, hospitals could detect outbreaks earlier, isolate patients faster, and drastically reduce the spread of communicable diseases.

Key points

  • The RATE algorithm uses artificial intelligence to analyze biometric data from commercial wearables like Garmin watches and Oura rings.
  • By tracking subtle changes in heart rate variability and skin temperature, the system detects the body's early immune response.
  • A peer-reviewed study demonstrated the technology can predict a symptomatic COVID-19 infection an average of 2.3 days before a diagnostic test.
  • The Department of Defense is expanding the program to thousands of new personnel to maintain unit readiness and prevent outbreaks.
  • Researchers are actively working to transition the predictive technology into civilian hospitals to monitor vulnerable patients.
48 hours
Average early detection time before symptoms
165
Biomarkers analyzed in the initial training dataset
41,000
Hospital-acquired infection cases used to train the AI
2.3 days
Average prediction time prior to diagnostic testing in the Nature study
$10 million
APFIT funding to expand the program to new military cohorts

Throughout military history, infectious disease has often proven to be a more formidable adversary than enemy combatants. From the influenza outbreaks of World War I to the rapid spread of modern pathogens in confined environments like naval vessels and barracks, the invisible threat of illness routinely degrades unit readiness and operational capacity. Traditionally, military medicine has been forced into a reactionary posture: waiting for a service member to report symptoms, administering a diagnostic test, and then attempting to contain the subsequent outbreak through quarantine. This lag time between exposure and symptom onset—the pre-symptomatic window—has historically been the critical vulnerability in force health protection.[4]

That paradigm is currently undergoing a radical transformation driven by the convergence of artificial intelligence and commercial wearable technology. The Department of Defense is rapidly scaling a predictive health monitoring system designed to detect infections days before a patient ever feels a tickle in their throat or a spike in their temperature. Known as the Rapid Analysis of Threat Exposure (RATE) algorithm, the initiative represents a fundamental shift from reactionary treatment to proactive, predictive medicine. By continuously analyzing subtle biometric data, the military is effectively installing a "check-engine light" for the human body.[1]

The origins of the RATE program predate the global pandemic, rooted in a 2018 collaboration between the Defense Threat Reduction Agency (DTRA), the Defense Innovation Unit (DIU), and healthcare technology giant Philips. The initial objective was to predict hospital-acquired infections among patients already under intensive clinical care. To build the foundational artificial intelligence, researchers utilized a massive proprietary dataset from Philips, training the machine learning models on 165 distinct biomarkers extracted from over 41,000 documented cases of hospital-acquired infections.[4]

When the COVID-19 pandemic paralyzed global operations in early 2020, the defense establishment recognized an urgent need to lateral this hospital-grade predictive capability into the field. The challenge was immense: researchers had to transition an algorithm built on high-fidelity, invasive clinical monitors to function reliably using the relatively noisy data generated by commercial off-the-shelf (COTS) wearable devices. The DIU and Philips rapidly adapted the RATE system to ingest data from consumer-grade smartwatches and smart rings, launching a massive prospective study across the active-duty workforce.[1]

How the Rapid Analysis of Threat Exposure (RATE) algorithm processes biometric data.
How the Rapid Analysis of Threat Exposure (RATE) algorithm processes biometric data.

The biological premise underlying the RATE algorithm is that the human immune system begins fighting an invading pathogen long before clinical symptoms manifest. When a person is exposed to an infectious agent, their physiology undergoes microscopic shifts—alterations in resting heart rate, subtle variations in skin temperature, and changes in heart rate variability. While these fluctuations are entirely imperceptible to the individual, they create a distinct biometric signature. The RATE algorithm continuously monitors these data streams, identifying the mathematical patterns that indicate an escalating immune response.[2]

The empirical evidence supporting the system's efficacy was cemented in a comprehensive 2022 study published in the peer-reviewed journal Nature Scientific Reports. Analyzing data from thousands of military personnel, the researchers demonstrated that the algorithm could accurately predict a symptomatic COVID-19 infection an average of 2.3 days prior to a positive diagnostic test. In some asymptomatic cases, the system flagged the physiological anomaly up to six days before the infection would have otherwise been detected.[1][2]

The empirical evidence supporting the system's efficacy was cemented in a comprehensive 2022 study published in the peer-reviewed journal Nature Scientific Reports.

"RATE goes against our mental model for disease," explained Air Force Lt. Col. Jeff Schneider, the DIU's program manager for the initiative. "Normally, you wait until you have symptoms to do anything. With RATE, we have the ability to tell you something's coming before you feel anything." This "left-of-cough" awareness allows commanders to isolate potentially infectious personnel before they can unwittingly spread a pathogen through a unit, fundamentally altering the mathematics of disease transmission in close-quarters environments.

Following the successful validation of the prototype, the Department of Defense is now aggressively expanding the program. Backed by $10 million in funding from the Accelerate the Procurement and Fielding of Innovative Technologies (APFIT) initiative, the DIU is distributing 4,500 additional wearable devices to new cohorts across the military. This expansion includes equipping 360 first sergeants within the Air Combat Command, integrating the predictive health data directly into their daily readiness assessments and operational planning.[1]

The algorithm provides a 'left-of-cough' early warning, detecting physiological changes before clinical symptoms manifest.
The algorithm provides a 'left-of-cough' early warning, detecting physiological changes before clinical symptoms manifest.

Crucially, the RATE architecture is designed to be device-agnostic. While the current operational deployment relies heavily on Garmin smartwatches and Oura rings, the underlying data structure is being refined to accept inputs from a wide variety of commercial wearables. This "bring your own device" philosophy ensures that the military is not locked into a single hardware vendor and can continuously leverage the rapid advancements occurring within the consumer health technology sector.[1]

The RATE algorithm is not an isolated effort; it is part of a broader, sweeping initiative across the defense sector to utilize predictive analytics for force protection. The U.S. Army's Medical Research and Development Command has developed complementary systems like 2B-Cool, which uses smartwatch data to predict and prevent exertional heatstroke during high-intensity training, and 2B-Alert, which optimizes cognitive performance during periods of severe sleep deprivation.[3]

Similarly, RTI International recently detailed the development of AlphaWear, a high-resolution data capture platform funded by the Defense Advanced Research Projects Agency (DARPA) and the Joint Program Executive Office for Chemical, Biological, Radiological and Nuclear Defense. AlphaWear synthesizes physiological and behavioral data to simultaneously assess heat strain, infection risk, and mental health indicators, providing a holistic, real-time dashboard of a service member's overall resilience and operational viability.

As these predictive algorithms mature within the crucible of military operations, the technology is poised for a massive transition into civilian healthcare. Philips is actively exploring how the RATE system can be deployed in civilian hospitals to monitor vulnerable patients for early signs of sepsis or secondary infections. Furthermore, the ability to detect the onset of communicable diseases days in advance holds profound implications for global public health, offering a potential blueprint for containing future pandemics before they can exponentially scale.[4]

The predictive health initiative is designed to be device-agnostic, currently utilizing Garmin watches and Oura rings.
The predictive health initiative is designed to be device-agnostic, currently utilizing Garmin watches and Oura rings.

The widespread adoption of continuous biometric monitoring does introduce complex questions regarding data privacy and ownership. To mitigate these concerns, the military's current wearable programs operate on strict data-handling protocols. The biometric information processed by the RATE algorithm is de-identified and stored without direct attribution to the individual's name in the aggregate databases. Service members can access their personal "infection risk score" via a secure portal, ensuring the data serves as a tool for individual empowerment rather than mere surveillance.[4]

Ultimately, the successful deployment of the RATE algorithm represents a watershed moment in the evolution of medical technology. By transforming everyday consumer wearables into sophisticated early-warning systems, the defense sector has proven that the physiological data required to predict illness is already hiding in plain sight. As this technology transitions from military barracks to civilian life, it promises to rewrite the fundamental rules of disease management, offering humanity a vital head start against the invisible threats of tomorrow.[4]

How we got here

  1. 2018

    The Defense Threat Reduction Agency and Philips initiate a project to predict hospital-acquired infections using clinical data.

  2. June 2020

    The RATE algorithm is adapted for commercial wearables and deployed to active-duty military personnel during the COVID-19 pandemic.

  3. 2022

    Nature Scientific Reports publishes a peer-reviewed study confirming the algorithm's ability to predict COVID-19 an average of 2.3 days before testing.

  4. April 2023

    The Department of Defense awards $10 million in APFIT funding to expand the wearable program to thousands of additional service members.

Viewpoints in depth

Military Readiness Planners

Focus on maintaining operational capacity and preventing unit-wide outbreaks.

For defense officials, the primary value of predictive health monitoring is force preservation. In confined environments like submarines, barracks, or deployed forward operating bases, a single asymptomatic carrier can rapidly degrade an entire unit's combat effectiveness. By utilizing the RATE algorithm, commanders gain a 'left-of-cough' advantage, allowing them to isolate potentially infected personnel before the pathogen spreads, thereby maintaining the mathematical certainty of their troop levels and operational readiness.

Medical Researchers

Focus on the empirical validation of predictive models and the shift to proactive medicine.

The scientific community views the RATE algorithm as a crucial proof-of-concept for the future of proactive healthcare. Researchers emphasize that the 2022 Nature Scientific Reports study validated the hypothesis that subtle, pre-symptomatic physiological shifts—such as changes in heart rate variability—can be reliably quantified by consumer-grade sensors. This empirical success paves the way for a broader medical paradigm shift, moving away from diagnostic testing after an illness has taken hold, toward continuous, non-invasive monitoring that anticipates physiological decline.

Privacy & Ethics Advocates

Focus on the implications of continuous biometric monitoring and data ownership.

While acknowledging the profound health benefits, privacy advocates caution against the normalization of continuous biometric surveillance by employers or government entities. They argue that as these predictive algorithms transition into the civilian workforce, strict regulatory frameworks must be established to prevent biometric data from being weaponized for discriminatory practices, such as penalizing employees for predicted illnesses or utilizing health data to assess job performance. Ensuring that data remains de-identified and opt-in is considered paramount.

What we don't know

  • It remains unclear how accurately the algorithm can predict entirely novel, unstudied pathogens that may trigger different physiological immune responses.
  • The long-term privacy implications and regulatory frameworks for deploying continuous biometric monitoring in civilian corporate environments have yet to be fully resolved.
  • We do not yet know if the widespread use of predictive health alerts might lead to 'alert fatigue,' causing individuals to ignore early warnings over time.

Key terms

RATE Algorithm
Rapid Analysis of Threat Exposure, an AI model that predicts infections using biometric data.
Biomarker
A measurable indicator of a biological state or condition, such as heart rate variability or skin temperature.
Pre-symptomatic
The period after an individual has contracted an infection but before they exhibit noticeable clinical symptoms.
COTS
Commercial Off-The-Shelf, referring to consumer-grade products (like standard smartwatches) used in military or enterprise applications.

Frequently asked

How does the RATE algorithm predict an infection before symptoms appear?

When the body is exposed to an infectious agent, it begins fighting the pathogen before noticeable symptoms occur. RATE detects the subtle physiological changes—such as shifts in heart rate variability and skin temperature—caused by this early immune response.

What kind of wearable devices does the military use for this program?

The program currently utilizes commercial off-the-shelf (COTS) devices, primarily Garmin smartwatches and Oura smart rings, though the algorithm is designed to eventually be device-agnostic.

Can this technology predict specific diseases like COVID-19?

While heavily tested during the COVID-19 pandemic, the algorithm detects the body's general immune response to a wide array of infectious diseases, rather than identifying the specific pathogen.

Sources

Source coverage

4 outlets

3 viewpoints surfaced

Military Readiness Planners 40%Medical Researchers 40%Privacy Advocates 20%
  1. [1]Defense Innovation UnitMilitary Readiness Planners

    DoD Expands Wearable Technology for Infectious Disease Detection

    Read on Defense Innovation Unit
  2. [2]Nature Scientific ReportsMedical Researchers

    Early detection of COVID-19 using wearables

    Read on Nature Scientific Reports
  3. [3]U.S. ArmyMedical Researchers

    Predictive Analytics for Soldier Readiness

    Read on U.S. Army
  4. [4]Factlen Editorial TeamPrivacy Advocates

    Synthesis by Factlen editorial team

    Read on Factlen Editorial Team
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