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FDA and CDC Investigate Cyclospora Outbreak Linked to Mexican Iceberg Lettuce Amid 10,900 Illnesses

US health officials have officially closed their investigation into the record-setting cyclosporiasis outbreak linked to iceberg lettuce, which sickened nearly 13,000 people without a definitive farm origin being identified.

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The CDC has closed its investigation into the record-setting cyclospora outbreak linked to iceberg lettuce.From: CDC Declares End to Largest Cyclospora Outbreak in US History at 12,883 Cases

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The 2026 outbreak reached 12,883 confirmed cases, dwarfing previous domestic cyclospora events.From: CDC Declares End to Largest Cyclospora Outbreak in US History at 12,883 Cases ·
The outbreak has reached nearly 11,000 confirmed cases across 17 states, though the contaminated lettuce is no longer in circulation.From: FDA and CDC Investigate Cyclospora Outbreak Linked to Mexican Iceberg Lettuce Amid 10,900 Illnesses ·
Case numbers continue to rise due to the inherent lag time in parasite detection and reporting, not ongoing exposure.From: FDA and CDC Investigate Cyclospora Outbreak Linked to Mexican Iceberg Lettuce Amid 10,900 Illnesses ·
Investigators traced the contaminated lettuce through complex supply chains but could not identify the origin farm.From: CDC Declares End to Largest Cyclospora Outbreak in US History at 12,883 Cases ·
Major foodservice operators and restaurants moved quickly to pull the implicated shredded lettuce from their menus to protect consumers.From: FDA and CDC Investigate Cyclospora Outbreak Linked to Mexican Iceberg Lettuce Amid 10,900 Illnesses ·

Timeline

September 2026

  1. CDC Declares End to Largest Cyclospora Outbreak in US History at 12,883 Cases

August 2026

  1. FDA and CDC Investigate Cyclospora Outbreak Linked to Mexican Iceberg Lettuce Amid 10,900 Illnesses